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Fig. 2

ID

ZDB-FIG-220726-86

Publication

Zada et al., 2022 - TFAP2B Haploinsufficiency Impacts Gastrointestinal Function and Leads to Pediatric Intestinal Pseudo-obstruction

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Fig. 2

TFAP2B transcript and protein expression analysis. (A) qRT-PCR analysis of TFAP2B transcript levels of WT, c.706 C > T, c.898 C > T, c.1144 C > T, and exon 4 deletion expression constructs show no statistically significant difference among the samples normalized to GAPDH and b-Actin. (B) Western blot analysis of all tested variants shows absence of protein products for the syndromic craniosynostosis variant (c.1144 C > T) and PIPO variant (del Exon 4). Protein products are still detectable for the Char syndrome variants (c.706 C > T and c.898 C > T). A Myc-tag antibody was used to visualize TFAP2B protein levels.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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