FIGURE

Fig. 6

ID

ZDB-FIG-220701-19

Publication

Mesika et al., 2022 - NGLY1 Deficiency Zebrafish Model Manifests Abnormalities of the Nervous and Musculoskeletal Systems

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Fig. 6

Locomotion analysis. (A?C) Quantification of swimming distance of ngly1 ^(+/+) and ngly1 ^(?/?) larvae for 5 min at various consecutive light conditions: light-dark-light. Each experiment was repeated 3 times, n = 91, t-test, **p < 0.01, ***p < 0.001. (D) Quantification of swimming distance in larvae (6dpf) at normal conditions. C: control, t-test (n = 12 in each group, ***p < 0.001). (E) Quantification of swimming distance after acetic acid (pH = 3.8) treatment-ngly1 ^(+/+) compared to ngly1 ^(?/?) from one independent experiment. aa: acetic acid, t-test (n = 36 in each group, *p < 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ngly1^{zf3678/zf3678} (AB)
Conditions:	chemical treatment by environment: acetic acid lighting conditions
Observed In:	swimming behavior
Stage:	Day 6

Phenotype Detail

Acknowledgments

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