FIGURE

Fig. 9

ID
ZDB-FIG-220622-121
Publication
Djokic et al., 2022 - Novel Quorum Quenching YtnP Lactonase From Bacillus paralicheniformis Reduces Pseudomonas aeruginosa Virulence and Increases Antibiotic Efficacy in vivo
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Fig. 9

Pseudomonas aeruginosa PAO1 tail wound infection was successfully eliminated by applying YtnP-ZP1 in combination with tobramycin. Wild-type zebrafish embryos were decapitated at 72 hpf and infected with 4–6 × 107 cells of P. aeruginosa PAO1-GFP. After 1–2 h of recovery, wounded embryos were treated with tobramycin, lactonase, or their combination. Individual treatment with enzyme or antibiotic partially eliminated infection from the wounded tail, while combination treatment with lactonase and tobramycin was more effective resulting in no visible bacterial infection (lack of fluorescence).

Expression Data

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Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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