FIGURE

Fig. 5

ID

ZDB-FIG-220607-34

Publication

Varela et al., 2022 - Cdkl5 mutant zebrafish shows skeletal and neuronal alterations mimicking human CDKL5 deficiency disorder

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Fig. 5

Skeletal development of cdkl5^sa21938 mutants with 14 dpf. (A) Representative images of the wild-type (WT) and homozygous (cdkl5^-/-) larvae double-stained with alcian blue and alizarin red. Scale bar?=?0.5 mm. (B) Number of mineralized vertebrae in cdkl5^?/? (n?=?58) and WT (n?=?54) larvae. Values are represented as median with interquartile range. Statistical analysis was performed using Mann?Whitney. (C) Percentage of fish with mineralized caudal fin rays. Statistical analysis was performed using the Chi-square test. **** indicate p?<?0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cdkl5^{sa21938/sa21938} (AB)
Observed In:	caudal fin principal ray bone mineralization vertebra bone mineralization
Stage:	Days 14-20

Phenotype Detail

Acknowledgments

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