FIGURE

Figure 4

ID

ZDB-FIG-220512-4

Publication

Chen et al., 2022 - Upregulation of PNCK Promotes Metastasis and Angiogenesis via Activating NF-κB/VEGF Pathway in Nasopharyngeal Carcinoma

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Figure 4

The activity of the NF-κB/VEGF signaling pathway is upregulated by PNCK overexpression in NPC cells. (a) Dot plot of Ingenuity Pathway Analysis (IPA) shows significant changes in NF-κB and VEGF signaling pathways. (b) GSEA shows negative regulation of NF-κB transcription factor activity enriched in the PNCK-low expression phenotype. (c) WB was used to investigate the P65, p-P65, p-IκB, GAPDH, and Histone-H3. The correlation between PNCK and VEGFA in (d) internal cohort and (e) GSE102349 cohort. (f, g) The expression of VEGFA levels in NPC cells was evaluated by PCR and WB.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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