FIGURE

Figure 1

ID

ZDB-FIG-220309-12

Publication

Banerjee et al., 2022 - Vision and sensorimotor defects associated with loss of Vps11 function in a zebrafish model of genetic leukoencephalopathy

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Figure 1

Schematic representation comparing the lengths and interaction domains of human VPS11 and VPS11(C846G) with zebrafish Vps11(plt) and Vps11(−/−). (A) Top: Schematic representation of full-length human VPS11 protein, showing multiple highly-conserved protein domains. Lines above show the putative interactive domains with other Vps effectors based largely on work done in yeast. Below: Schematic representations of human VPS11(C846G), zebrafish Vps11(plt), and zebrafish Vps11(−/−), resulting in presumptively shorter truncated protein products. Note that zebrafish and human sequences do not show 100% nucleic acid identity, but do show conserved protein domains.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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