IMAGE

Figure 1

ID: ZDB-IMAGE-220309-12
Publication: Banerjee et al., 2022 - Vision and sensorimotor defects associated with loss of Vps11 function in a zebrafish model of genetic leukoencephalopathy
All Figures: Figures for Banerjee et al., 2022

Image

Figure Caption

Figure 1

Schematic representation comparing the lengths and interaction domains of human VPS11 and VPS11(C846G) with zebrafish Vps11(plt) and Vps11(−/−). (A) Top: Schematic representation of full-length human VPS11 protein, showing multiple highly-conserved protein domains. Lines above show the putative interactive domains with other Vps effectors based largely on work done in yeast. Below: Schematic representations of human VPS11(C846G), zebrafish Vps11(plt), and zebrafish Vps11(−/−), resulting in presumptively shorter truncated protein products. Note that zebrafish and human sequences do not show 100% nucleic acid identity, but do show conserved protein domains.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.