FIGURE

Fig. 5

ID

ZDB-FIG-220107-32

Publication

Park et al., 2021 - Flavin Adenine Dinucleotide Depletion Caused by electron transfer flavoprotein subunit alpha Haploinsufficiency Leads to Hepatic Steatosis and Injury in Zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Riboflavin supplementation suppresses oxidative stress in etfa+/− mutant livers. Adult zebrafish were exposed to riboflavin, as in Fig. 4. (A) Relative ROS, (B) GSH levels, and (C) MDA levels in wild-type and etfa+/− livers from untreated or riboflavin-treated adult zebrafish were measured (see Materials and Methods) (n = 6 per group). Relative mRNA expression of (D) NADPH oxidases and (E) oxidative stress-responding genes was measured (see Materials and Methods; three livers were used to make normalized RNA; *P < 0.05, **P < 0.005). Abbreviations: gstp1/2, glutathione S transferase pi 1 and 2; ho-1a, heme oxygenase 1a; nrf2, nuclear factor erythroid 2-related factor 2; prdx4, peroxiredoxin 4.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Hepatol Commun