FIGURE

Fig 3

ID

ZDB-FIG-211201-3

Publication

Gibson et al., 2021 - Commensal bacteria augment Staphylococcus aureus infection by inactivation of phagocyte-derived reactive oxygen species

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Fig 3

Augmenting material protects S. aureus from ROS in vitro.

A Reactive oxygen species generated in the oxidative burst, ROS highlighted in red are examined B-D Following ROS exposure, percentage survival of S. aureus alone (5x10⁴ CFU/mL), or with M. luteus PGN (1.25 mg) B hydrogen peroxide (n = 3, error bars show mean +/- SD, one-way ANOVA test with Tukey?s post hoc test) *p<0.05 C sodium hypochlorite (n = 3, error bars show mean +/- SD, one-way ANOVA test with Tukey?s post hoc test), **p<0.01; ***p<0.005 D peroxynitrite (n = 3, error bars show mean +/- SD, one-way ANOVA test with Tukey?s post hoc test), ***p<0.005; ****p<0.0001 E Following sodium hypochlorite exposure, percentage survival of S. aureus alone (5x10⁴ CFU/mL), with heat-killed M. luteus (equivalent of 5x10⁶ CFU/mL) or ROS killed M. luteus (equivalent of 5x10⁶ CFU/mL) (n = 3, error bars show mean +/- SD, one-way ANOVA test with Tukey?s post hoc test), *p<0.05 F-G Following ROS exposure, percentage survival of S. aureus alone (5x10⁴ CFU/mL), with heat-killed M. luteus (equivalent of 1.25x10⁸ CFU/mL), or ROS killed M. luteus (equivalent of 1.25x10⁸ CFU/mL) F hydrogen peroxide (n = 3, +/-SD, one-way ANOVA test with Tukey?s post hoc test), *p<0.05; ****p<0.0001 G peroxynitrite (n = 3, +/-SD one-way ANOVA test with Tukey?s post hoc test), *p<0.05; **p<0.003.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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