FIGURE
Figure 1
- ID
- ZDB-FIG-211201-180
- Publication
- Rudzinska-Radecka et al., 2021 - The Anti-Tumoral Potential of Phosphonate Analog of Sulforaphane in Zebrafish Xenograft Model
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Figure 1
Schematic representation of molecular pathways targeted by isothiocyanates (ITCs) in cancer cells. ITCs exert their anti-tumor activities through various mechanisms, including (i) regulation of the epigenetic machinery, (ii) prevention of metastasis and angiogenesis, (iii) apoptosis via reactive oxygen species-initiated mitochondrial dysfunction (iv) inhibition of cell growth by causing cell cycle arrest and inducing cell death and (v) modulation of phase I and II enzymes [4]. The concentration in which ITCs present biological activity depends on chemical modifications and cell types. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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