FIGURE

Figure 5

ID

ZDB-FIG-211120-93

Publication

Cheng et al., 2021 - 1,25(OH)₂D₃ Inhibited Ferroptosis in Zebrafish Liver Cells (ZFL) by Regulating Keap1-Nrf2-GPx4 and NF-κB-hepcidin Axis

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Figure 5

Volcano plots of differently expressed genes (DEGs) (A), chord diagram of signal pathways related to iron ion transport and metal ion transport (GO term) (B), and Top-20 pathways with the most significant enrichment by KEGG (C). All the DEGs were screened according to |log2(Fold change)| ? 1 and p-adjust < 0.05. In the volcano plots, the red dots represent upregulated genes, blue dots represent downregulated genes, and grey dots represent genes that do not meet the above screening conditions. Different colors in the chord graphs represent different signaling pathways, and log2(Fold change) value is shown in color gradient. In picture (C), the red bar represents the value of ?log10(p-adjust) and the light blue line represents the number of genes in the corresponding signaling pathway.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.