FIGURE

Figure 5

ID

ZDB-FIG-211103-40

Publication

Lim et al., 2021 - The LAMMER Kinase, LkhA, Affects Aspergillus fumigatus Pathogenicity by Modulating Reproduction and Biosynthesis of Cell Wall PAMPs

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Figure 5

Alveolar macrophage response to ΔAflkhA conidia. MH-S murine alveolar macrophages were challenged with a three-fold concentration of WT and ΔAflkhA conidia and then incubated for 4 hrs at 37°C in an atmosphere of 5% CO₂. (A) Microscopic analysis of the uptake of the fungal conidia by MH-S macrophages. External conidia (black arrows) were stained by calcofluor white (1 μg/mL in DPBS). White arrows indicate conidia endocytosed by macrophage cells. (B) Phagocytosis of conidia. The percentage of macrophages containing more than one ingested conidia was counted (n = 18). (C) Phagocytosis index. The average number of indigested conidia per macrophage (c/m) was calculated (n = 40). Statistical analysis was performed using the student’s t-test. ***P < 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Infect Microbiol