FIGURE

Figure 5

ID

ZDB-FIG-211029-247

Publication

Glazer et al., 2021 - Developmental Exposure to Low Concentrations of Methylmercury Causes Increase in Anxiety-Related Behaviour and Locomotor Impairments in Zebrafish

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Figure 5

HPI-axis gene expression in larvae (left column) and adult brains (right column). Relative quantification of grα (top row), mr (middle row) and crf (bottom row) was measured in 4, 5, and 6 dpf larvae (left column, larval stage) and in the brains of developmentally exposed adult fish that were behaviourally tested, using RT-qPCR. β-actin was used as an internal standard. The ΔΔCt method was used to determine the fold change in gene expression. Subject numbers: larvae = 3; adult brains, 0 nM = 12–14, 5 nM = 6, 10 nM = 6, 15 nM = 7, 30 nM = 11–12. Significant differences from vehicle control are marked with an asterisk. Lower-case letters in the middle row indicate differences between means within 4 dpf and 6 dpf larvae. * p < 0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.