FIGURE

Fig. 3

ID

ZDB-FIG-211009-8

Publication

Jang et al., 2021 - Epigenetic dynamics shaping melanophore and iridophore cell fate in zebrafish

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Fig. 3

Motif enrichment analysis reveals alx transcription factor family as putative regulator of iridophore development. a, b Heatmaps representing motif enrichment, gene expression, and gene fold change of transcription factors when comparing late NCC differentiation into melanophores (a) and iridophores (b). c Bar plots representing frequency and distribution of iridophore-associated DM/ARs with a particular TF motif. d Heatmaps representing DNA methylation and ATAC signal across iridophore-associated DM/ARs with specific TF motifs. e ATAC-seq footprint signatures of alx transcription factor candidates. f Model of guanine synthesis cycle. Iridophore-specific DEGs are shown in bold. Boxes above DEGs are color-coded based on detection of CREs containing TF motifs within 50 kb of DEG promoters

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	j329Tg/j329Tg
Observed In:	iridophore positive regulation of gene expression, epigenetic melanocyte positive regulation of gene expression, epigenetic neural crest cell positive regulation of gene expression, epigenetic regulation of iridophore differentiation regulation of melanocyte differentiation
Stage Range:	10-13 somites to Day 6

Phenotype Detail

Acknowledgments

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