FIGURE
Figure 8
- ID
- ZDB-FIG-211002-92
- Publication
- Chen et al., 2021 - Heteronemin Suppresses Lymphangiogenesis through ARF-1 and MMP-9/VE-Cadherin/Vimentin
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Figure 8
Schema of heteronemin-induced anti-lymphangiogenic mechanism in human lymphatic endothelial cells. This study reveals heteronemin as a promising anti-lymphangiogenic agent. Heteronemin may possess anti-lymphangiogenesis effect by reducing VEGFR-3 and its downstream NF-κB p65 and MEK/ERK signaling pathways and ARF-1, as well as the induction of VE-cadherin and the reduction in MMP-9 and vimentin, which is associated with EndoMT, in human lymphatic endothelial cells. T-shaped lines indicate inhibition. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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