Figure 6
- ID
- ZDB-FIG-211002-35
- Publication
- Selvaraju et al., 2021 - Sensitivity of Acute Myelocytic Leukemia Cells to the Dienone Compound VLX1570 Is Associated with Inhibition of the Ubiquitin-Proteasome System
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Figure 6. Activity of VLX1570 in the zebrafish embryo model; (A) survival of zebrafish embryos exposed to the indicated concentrations of VLX1570 for 0–72 or 72–120 h; (B) examples of results obtained using labeled AML cells injected into zebrafish embryos followed by treatment with VLX1570; (C) effect of 1 µM VLX1570 on the growth and dissemination of injected AML cell lines in zebrafish embryos (student’s t test, ** p ≤ 0.01, *** p ≤ 0.001); and (D,E) effect of 1 µM VLX1570 on the growth and dissemination of injected primary AML cells in zebrafish embryos (student’s t test, * p ≤ 0.05, ** p ≤ 0.01). |