FIGURE

Fig 6

ID
ZDB-FIG-210912-6
Publication
Minenkova et al., 2021 - Is impaired energy production a novel insight into the pathogenesis of pyridoxine-dependent epilepsy due to biallelic variants in ALDH7A1?
Other Figures
(all 6)
All Figure Page
Back to All Figure Page
Fig 6

mtDNA amount is not significantly reduced in aldh7a1 knock-out zebrafish.

qPCR graph of mtDNA amount from wildtype (Wildtype, black circles) and aldh7a1 homozygous knock-out (aldh7a1 knock-out, grey squares) zebrafish embryos, demonstrating only a slight reduction in mtDNA copy number in knock-out relative to the wildtype embryos. Each dot represents DNA extracted from 5 embryos. The amounts of mtDNA from knock-out and wildtype embryos were normalized to the average mtDNA amount from the wildtype embryos. p value is calculated by an unpaired two-tailed student t-test. Error bars, mean and SD.
Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Days 7-13

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.