Figure 6

Multiple sequence alignment and three-dimensional structures predicted by (PS)2-v2: protein structure prediction server for the highly conserved lncRNA-encoded peptides among zebrafish, humans, and mice. Pineal gland lncRNA-encoded peptides (A–L) and testis lncRNA-encoded peptides (M–P). The asterisk symbols (A,E,I,M) depict the identical amino acids among the peptides encoded by zebrafish lncRNAs (ZFLNCT01316_1, ZFLNCT17094_10, ZFLNCT19216_1, and DANIO_RERIO_NEWGENE_8529_1), as well as their corresponding mouse orthologs (BF470940.1_Mouse, BX515373_mouse, GH454583_mouse, and CB521528.1_Mouse) and human orthologs (AV726556_human, DA433582_human, DA369397_human, and BU146414.1_Human). The 3D models of the peptides (B–D,F–H,J–L,N–P) represent the conservation of α-helix (pink or purple motif structure), β-strand (yellow layered band), and random coils (white or blue thread) among zebrafish, humans, and mice with known domains from the Protein Data Bank, such as, B (2adcA), C (2adcA), D (2adcA), F (1nkpB), G (1nkpB), H (1nkpB), J (1wyoA), K (1wyoA), L (1wyoA), N (1u19A), O (2vt4B), and P (1xioA).