FIGURE

Figure 2.

ID

ZDB-FIG-210717-31

Publication

Chowdhury et al., 2021 - Histopathological assessment of laterality defects in zebrafish development

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Figure 2.

Cardiac looping defects and hypoplastic ventricle. (A) 3D SPIM imaging of the developing endocardium of Tg(fli1:EGFP) zebrafish embryos revealed cardiac defects in 50 hpf embryos from multiple in-crosses and cold shock: D-loop (a), incomplete loop (b), L-loop (c), and unloop (d) hearts. A, atrium; V, ventricle. Scale bar, 50 µm. (B) Total cell number in the endocardium of Tg(fli1:EGFP) zebrafish embryos at 50 hpf was counted using the 3D images (n = 6 of embryos with D-loop, n = 17 of embryos with laterality defects). Endocardial ventricles show more severe hypoplasia in the experimental embryos (E) compared with that in controls (C). Values are presented as mean ± SEM of total cell numbers. **P< .001 by two-sample Student’s t-test.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Animal Cells Syst (Seoul)