FIGURE

FIGURE 2

ID

ZDB-FIG-210630-31

Publication

Ji et al., 2021 - Protective Effect of Chlorogenic Acid and Its Analogues on Lead-Induced Developmental Neurotoxicity Through Modulating Oxidative Stress and Autophagy

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FIGURE 2

Micrographs, average toxicity scores, and malformation rate. (A) Representative images of toxicity score from 0 to 4 at 120 hpf. Zebrafish malformation was scored from level 0 to level 4.0, zebrafish developed normally; 1–3, zebrafish had slight-to-severe defects; 4, embryonic lethality. Two images for each of semiquantitative toxicity scoring indicate that both of these abnormalities are ranked as the same toxicity score (scale bar, 500 μm). (B) Average toxicity score at 120 hpf (n = 6); ^***p < 0.001 vs. control and ^#p < 0.05, ^##p < 0.01 vs. Pb. (C) Pb-induced phenotypic defects and malformation rate (n = 15); ^***p < 0.001 vs. control and ^#p < 0.05, ^##p < 0.01 vs. Pb.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Conditions:	chemical treatment by environment: lead diacetate chemical treatment by environment: 4-O-trans-caffeoylquinic acid chemical treatment by environment: chlorogenic acid chemical treatment by environment: lead diacetate
Observed In:	whole organism
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Mol Biosci