FIGURE

Fig 6

ID

ZDB-FIG-210519-53

Publication

McCluskey et al., 2021 - A complex genetic architecture in zebrafish relatives Danio quagga and D. kyathit underlies development of stripes and spots

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Fig 6

Chromosomal regions associated with pattern and size metrics in backcross individuals.

(A) Crossing schemes for mapping variation in two independent families, BC_a and BC_b (see main text). (B–C) Log odds scores of example QTL (BC_a) for melanophore spacing (nearest neighbor distance, log₂(DV:AP variation), and number of melanophore elements across 25 chromosomes. Variation segegrating between species in blue and within D. kyathit in red. Dashed lines indicate q = 0.05 false discovery thresholds and asterisks indicate peak LOD scores. (E) Summary of regions associated with pattern variation and size in the same family referenced in B–C (BC_a), and defined by F_ST values for phenotypically extreme individuals from a second family (BC_b; see main text). Regions highlighted have peaks (q<0.05, LOD≥4) marked by vertical bars and widths defined by positions 1.5 LOD lower than peaks. Percents of phenotypic variance explained by QTL (%var) are indicated at right. Small, vertical hash marks on chromosomes denote BC_a maternal D. kyathit marker loci and positions of several genes having roles in pigment pattern formation in D. rerio are indicated as well.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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