FIGURE

Figure 3

ID

ZDB-FIG-210428-8

Publication

Nogaret et al., 2021 - A Novel Infection Protocol in Zebrafish Embryo to Assess Pseudomonas aeruginosa Virulence and Validate Efficacy of a Quorum Sensing Inhibitor In Vivo

Other Figures

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Figure 3

Validation of bath infection model with a known antibiotic. (A) Kaplan?Meier representation of the survival of injured zebrafish embryos bath infected with PAO1 strain at approximately 10⁸ CFU/mL and treated with ciprofloxacin 50 �g/mL or hydrochloric acid 0.2 mM (negative control) 2 hours after infection. (B) Kaplan?Meier representation of the survival of injured zebrafish embryos bath infected with PAO1 strain at approximately 5 � 10⁷ CFU/mL and treated with ciprofloxacin 1 �g/mL or hydrochloric acid 0.5 mM (negative control) 2 hours after infection. Pools of three biologically independent replicates (with 20 embryos) are shown for each survival curve. *** p < 0.001; ** p < 0.01.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	bacterial treatment by exposure to environment: Pseudomonas aeruginosa, chemical treatment by environment: ciprofloxacin, transection: caudal fin
Observed In:	whole organism
Stage Range:	Pec-fin to Day 4

Phenotype Detail

Acknowledgments

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