FIGURE

Fig. 4

ID

ZDB-FIG-210426-19

Publication

Bieczynski et al., 2020 - Chemical effects on dye efflux activity in live zebrafish embryos and on zebrafish Abcb4 ATPase activity

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Fig. 4

(A–C) Correlations of the maximum measured effect levels for each compound in the different tests: (A) maximum inhibition of stimulated Abcb4 ATPase activity vs. the maximum stimulation of the basal Abcb4 ATPase activity; (B) maximum stimulation of the basal Abcb4 ATPase activity vs. the maximum observed increase in fluorescence in the dye efflux assay; and (C) maximum inhibition of stimulated Abcb4 ATPase activity vs. the maximum observed increase in fluorescence in the dye efflux assay. Each compound is represented by a data point. Pearson’s correlation parameters are shown in the respective graphs. Linear regressions are with 95% confidence intervals. APM, azinphos‐methyl; bA, basal ATPase activity; BpA, bisphenol A; CsA, cyclosporin A; ctrl, control; PHE, phenanthrene; sA, stimulated ATPase activity. Equations for linear regressions are as follows: (a) y = −0.06692x + 53.66; (b) y = 0.6272x + 82.25; and (c) y = 0.09262x + 58.07.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ FEBS Lett.