FIGURE

Figure 4—figure supplement 1.

ID

ZDB-FIG-210414-47

Publication

Pronobis et al., 2021 - In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration

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Figure 4—figure supplement 1.

Interactome map of Rac1 and Cdc42.

(A) Analysis of known Rac1b interactors in cmlc2:birA2-GFP BioID2 data set. Except for Jupb, all known interactors were found to be increased during heart regeneration. Size of circles indicate fold change. Proteins are sorted clockwise after fold change from high to low. Gna13: guanine nucleotide binding protein alpha 13a (25.8-fold); Gab1: GRB2-associated binding protein 1 (8.34-fold); Ephb2: ephrin receptor B2 (5.72-fold); Pfn1: profilin 1 (3.25-fold); Arhgap21b: Rho GTPase activating protein 21b (2.65-fold); Wasla: WASP-like actin nucleation promoting factor a (2.5-fold); Ctnnd1: catenin δ1 (2.2-fold); Ctnna1: catenin α1 (1.68-fold); Flii: flightless I actin remodeling protein (1.72-fold); Jupb: junctional plakoglobin b (−192-fold). (B) Analysis of known Cdc42 interactors in cmlc2:birA2-GFP BioID2 data set. See (A) for fold changes of proteins found also in Rac1b interactome. Mapre1b: microtubule-associated protein EB 1b (200-fold); Anxa2a: annexin A2a (20.5-fold); Tln1: Talin 1 (7.56-fold); ROCK2a: Rho-associated, coiled-coil containing protein kinase 2a (5.05-fold); Ilk: integrin-linked kinase (3.91-fold); Msna: moesin a (1.9-fold).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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