Fig. 3
- ID
- ZDB-FIG-210408-4
- Publication
- Dai et al., 2021 - Fucoxanthin-rich fraction from Sargassum fusiformis alleviates particulate matter-induced inflammation in vitro and in vivo
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Efficacy of FxRF against inflammation induced by PM in RAW 264.7 macrophages (A), and analyses of RAW cell viability and intracellular ROS levels; (B) Western blot analyses of iNOS and COX-2 expressions; and (C) ELISA of PGE2 and pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α). Pre-seeded cells (1 × 105 cells/mL) were treated with different FxRF concentrations after 24 h and stimulated with PM after 30 min. Cells were harvested after 24 h to measure inflammatory mediators (COX-2 and PGE2) and pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α). Graphical representations are means ± SE based on three replications. *p < 0.05 and **p < 0.01 indicate that the values were significantly different from those for the PM-treated group. |