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FIGURE 2

ID

ZDB-FIG-210324-16

Publication

Zang et al., 2021 - 10-Gingerol Suppresses Osteoclastogenesis in RAW264.7 Cells and Zebrafish Osteoporotic Scales

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FIGURE 2

10-gingerol suppresses osteoclastogenesis in RAW264.7 cells. (A) Representative images of sRANKL-treated RAW264.7 cells with 6-, 8-, or 10-gingerol. Each treatment was carried out at 2.5 μM. Red indicates the TRAP-stained area. The lower panels show the magnified images of sRANKL-treated RAW264.7 cells with or without gingerols. (B) Quantitative analysis of TRAP-positive multinucleated osteoclasts of (A). n = 8, error bars indicate SE; p values are calculated compared to vehicle with sRANKL. (C) Representative images for the pit formation assay with or without 10-gingerol. White indicates pits. (D) Bone resorption activities of panel (C) were quantified by the released FACS from the well bottom. n = 3, error bars indicate SE; ^∗p < 0.05 vs. vehicle with sRANKL.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol