ZFIN Image: Zang et al., 2021, FIGURE 2

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Figure Caption

FIGURE 2

10-gingerol suppresses osteoclastogenesis in RAW264.7 cells. (A) Representative images of sRANKL-treated RAW264.7 cells with 6-, 8-, or 10-gingerol. Each treatment was carried out at 2.5 μM. Red indicates the TRAP-stained area. The lower panels show the magnified images of sRANKL-treated RAW264.7 cells with or without gingerols. (B) Quantitative analysis of TRAP-positive multinucleated osteoclasts of (A). n = 8, error bars indicate SE; p values are calculated compared to vehicle with sRANKL. (C) Representative images for the pit formation assay with or without 10-gingerol. White indicates pits. (D) Bone resorption activities of panel (C) were quantified by the released FACS from the well bottom. n = 3, error bars indicate SE; ^∗p < 0.05 vs. vehicle with sRANKL.

Acknowledgments

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