FIGURE

Fig. 3.

ID

ZDB-FIG-210307-90

Publication

Li et al., 2020 - Tetraspanin18 regulates angiogenesis through VEGFR2 and Notch pathways

Other Figures

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Fig. 3.

Vessel regression in Tspan18 zebrafish morphants. (A) Intact ISV sprouting is observed at 26 hpf in Tspan18-deficient fish. (B) Confocal time-lapse microscopy of regressing ISVs (red arrows) in Tspan18-deficient fish. Numbers 1–4 indicate the order of ISVs. Yellow rectangle: corresponding section shown at higher magnification under the bottom. All larvae lateral view. Anterior is to the left. Scale bars: 50 μm. All experiments (A–B) were repeated at least three times and similar results were obtained.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	y1Tg + MO1-tspan18a (TU) y1Tg + MO2-tspan18a (TU)
Knockdown Reagents:	MO1-tspan18a MO2-tspan18a
Observed In:	blood vessel development intersegmental vessel intersegmental vessel sprouting angiogenesis
Stage Range:	Prim-5 to Prim-15

Phenotype Detail

Acknowledgments

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