FIGURE

Fig. 1.

ID

ZDB-FIG-210307-88

Publication

Li et al., 2020 - Tetraspanin18 regulates angiogenesis through VEGFR2 and Notch pathways

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Fig. 1.

Tspan18 expression in the cardiovascular system. The expression of Tspan18 and its paralogue Tspan12 was analyzed by RT-PCR in (A) human fetal tissues and (B) primary cultured endothelial cells and tumor cell lines. UASMC, umbilical artery smooth muscle cell; HUVEC, human umbilical vein endothelial cell; HUAEC, human umbilical artery endothelial cell; NC, negative control with no cDNA. (C) Quantitative RT-PCR analysis of Tspan18 expression at different times in zebrafish development (whole embryo). Expression was normalized to β–actin. (D) Whole-mount ISH of Tspan18 expression in the developing embryos. D is the cross section of C. DA, dorsal aorta; PCV, posterior cardinal vein; DLAV, dorsal longitudinal anastomotic vessels; ISV, intersegmental vessel; S, somites; NC, Notochord. All larvae lateral view unless indicated. Anterior is to the left. Scale bars:100 μm. All experiments (A–D) were repeated at least three times and similar results were obtained.

Expression Data

Gene:	tspan18a
Fish:	TU
Anatomical Terms:	dorsal aorta intersegmental vessel posterior cardinal vein trunk vasculature whole organism yolk
Stage Range:	1k-cell to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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