FIGURE

Fig. 1

ID

ZDB-FIG-210211-7

Publication

Smirnova et al., 2020 - Increased apoptosis, reduced Wnt/β-catenin signaling, and altered tail development in zebrafish embryos exposed to a human-relevant chemical mixture

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Fig. 1

Fig. 1. Timeline for the examination of effects on apoptosis and Wnt/?-catenin signaling in developing zebrafish. Apoptosis was studied by three methods, i.e., acridine orange staining (AO), terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL), and caspase 3-like activity assay (Caspase activity). Wnt/?-catenin signaling was assayed in the caudal fin using a transgenic zebrafish line, expressing an EGFP reporter at ?-catenin-regulated promoters. Caudal fin (CF) morphometry and standard length measurements were performed by image analysis. Transcript levels of genes related to apoptosis and oxidative stress were determined by qPCR.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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