FIGURE

Figure 6

ID

ZDB-FIG-210206-6

Publication

Noschka et al., 2021 - Unbiased Identification of Angiogenin as an Endogenous Antimicrobial Protein With Activity Against Virulent Mycobacterium tuberculosis

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Figure 6

Effect of Angie1 on macrophage viability and multiplication of intracellular Mtb. (A) Macrophages were incubated with Angie1 (PSL Heidelberg) at indicated concentrations for 24 h and viability was determined by the PrestoBlue™ assay. Bars represent the mean viability of macrophages (%) ± SD calculated from triplicates of three independent experiments. (B) Macrophages were infected with Mtb followed by incubation with Angie1 for 4 days. Mtb-multiplication was determined by plating cell lysates on 7H11 agar plates to determine and counting the number of CFU after 21 days of incubation. The graph gives the mean values ± SD of n-fold mycobacterial growth as compared to d0 for four independent donors.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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