FIGURE

FIGURE 2

ID

ZDB-FIG-210204-76

Publication

Wang et al., 2021 - The Bruton's Tyrosine Kinase Inhibitor Ibrutinib Impairs the Vascular Development of Zebrafish Larvae

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FIGURE 2

Vascular formation was perturbed in ibrutinib-treated embryos. (A) Confocal images of blood vessels in the brain and trunk of ibrutinib-treated Tg (kdrl:EGFP) embryos at 72 h post-fertilization (hpf). Scale bar: 100 μm. (B) The percentage of normal intersegmental vessels (ISVs) in embryos presented at (A); n = 10 for each group. (C) Confocal images of blood vessels in the trunk of embryos treated and washed at different stages. Scale bar: 100 μm. (D) The percentage of normal ISVs in embryos presented at (C); n = 10 for each group. Asterisks indicate significant differences (DMSO vs. ibrutinib), ***p < 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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