FIGURE

Figure 6

ID

ZDB-FIG-210128-13

Publication

Warchol et al., 2021 - Macrophages Respond Rapidly to Ototoxic Injury of Lateral Line Hair Cells but Are Not Required for Hair Cell Regeneration

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Figure 6

Selective depletion of macrophages in Tg(mpeg1:Gal4FF/UAS:NTR-mCherry) fish. Experiments utilized a transgenic fish line that expresses the bacterial enzyme NTR under the regulation of the Mpeg1 promoter (i.e., selectively in macrophages and microglia). Treatment of these fish with 0.1% DMSO did not affect the numbers of macrophages distributed within the posterior-most 500 μm of the spinal column (A,C). However, treatment for 24 h in 10 mM MTZ resulted in the nearly complete elimination of macrophages from this same region (B,C). Macrophage numbers remained low after 48 h recovery from MTZ treatment (C). Data obtained from 10 to 15 fish/treatment group.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.