FIGURE

Figure 6

ID

ZDB-FIG-210117-23

Publication

Moussouni et al., 2021 - Pseudomonas aeruginosa OprF plays a role in resistance to macrophage clearance during acute infection

Other Figures

All Figure Page

Back to All Figure Page

Figure 6

Effect of bafilomycin on the virulence of wild-type and ΔoprF mutant in zebrafish embryos. Embryos were infected with either wild-type or ΔoprF P. aeruginosa (2000–2500 CFU) in the hindbrain ventricle at 2 dpf or not infected (NI) (n = 60–70 for infected embryos and n = 45 for NI embryos, pool of three independent experiments). Survival curves of embryos treated with 50 nM bafilomycin (Bafil) (B) or treated with DMSO as control (A). Statistical significance was determined by log-rank test. Imaging (C) and quantification (D) of bacterial loads (fluorescence pixel counts) representative of two independent experiments at 20 hpi (n = 11–14). Each symbol represents individual embryo and horizontal lines indicate the median values. Statistical significance was determined by one-tailed Mann–Whitney’s test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.