FIGURE

FIGURE 7

ID
ZDB-FIG-210103-16
Publication
Narumi et al., 2020 - Chemical-Induced Cleft Palate Is Caused and Rescued by Pharmacological Modulation of the Canonical Wnt Signaling Pathway in a Zebrafish Model
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FIGURE 7

Summary of chemical-induced cleft palate. (A) Teratogen induces cleft palate by inhibition of the canonical Wnt signaling pathway. This defect is characterized by decreased proliferation and increased apoptosis in the zebrafish palate. Chemical-induced cleft palate is prevented by Wnt agonist treatment. (B) Application of a zebrafish model for suppressor screening as well as teratogenicity assay for chemicals.

Expression Data

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Antibody Labeling
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Acknowledgments
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