FIGURE

Fig. 4.

ID

ZDB-FIG-201231-4

Publication

Koleilat et al., 2020 - L-type voltage-gated calcium channel agonists mitigate hearing loss and modify ribbon synapse morphology in the zebrafish model of Usher syndrome type 1

Other Figures

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Fig. 4.

myo7aa^−/− larvae exhibit larger turning angles. Movement tracking of 5 dpf wild-type and myo7aa^−/− larvae at 2.5-min intervals, with 5 ms electric stimuli (50 mV) administered every 20 s. Ctrax software was used for video processing and MATLAB 2012b for video analysis. (A,B) myo7aa^−/− larvae have larger absolute smooth orientations (global change in body orientation) compared to wild-type larvae. Individual turning angles from a population of wild-type and myo7aa^−/− larvae were used to construct the lines (two-tailed t-test). Bold black lines in B represent the mean of the data set and error bars are 95% confidence intervals. Experiments were replicated five times for both wild-type and myo7aa^−/− mutants.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	myo7aa^{tc320b/tc320b}
Observed In:	response to electrical stimulus
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.