FIGURE

Figure 1

ID

ZDB-FIG-201130-30

Publication

Lai et al., 2020 - Duplicated dnmt3aa and dnmt3ab DNA Methyltransferase Genes Play Essential and Non-Overlapped Functions on Modulating Behavioral Control in Zebrafish

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Figure 1

Generation of dnmt3aa and dnmt3ab gene knockout (KO) zebrafish by using TALEN (transcription activator-like effector nuclease) genome-editing tool. (A) The location of TALEN right arm, spacer, and left arm on targeting zebrafish dnmt3aa and dnmt3ab genes are showed. (B) The Sanger sequencing dendrogram showed the sequence of wildtype, heterozygotes, and homozygotes of dnmt3aa (upper panel) and dnmt3ab (lower panel) mutants. (C) Three-dimension model predictions on the structure of wild type and Dnmt3aa and Dnmt3ab mutated proteins.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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