FIGURE

Figure 3

ID

ZDB-FIG-201130-33

Publication

Lai et al., 2020 - Duplicated dnmt3aa and dnmt3ab DNA Methyltransferase Genes Play Essential and Non-Overlapped Functions on Modulating Behavioral Control in Zebrafish

Other Figures

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Figure 3

Comparison of behavior endpoints among the wild-type, dnmt3aa, and dnmt3ab mutant fish during a 30-min novel tank exploration test. (A) Average speed, (B) freezing time movement ratio, (C) time in bottom duration, (D) number of entries to the top, (E) latency to enter the top, and (F) total distance traveled in the top fish tank were analyzed. The data are expressed as the median with interquartile range and analyzed by two-way ANOVA (n = 30 for wild type; n = 7 for dnmt3aa KO fish; n = 30 for dnmt3ab KO fish; ** p < 0.01, *** p < 0.005, ****, p < 0.0001). (G–I) The locomotion trajectories of a single fish of wild type, dnmt3aa KO, and dnmt3ab KO fish, right after introduced to a novel environment. (J–L) The locomotion trajectories of a single fish of the wild type, dnmt3aa KO, and dnmt3ab KO fish after 15 min of novel tank exposure.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dnmt3aa^cy53/cy53 dnmt3ab^cy54/cy54
Observed In:	whole organism exploration behavior whole organism swimming
Stage:	Adult

Phenotype Detail

Acknowledgments

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