FIGURE

Figure 2

ID

ZDB-FIG-200725-21

Publication

Toms et al., 2020 - Clinical and preclinical therapeutic outcome metrics for USH2A-related disease

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Figure 2

Visual acuity, EZ and hyperautofluorescent (hyperAF) ring measurements with age in USH2A patients. (A) and (B) Change in visual acuity over the observation period. (A) illustrates the change in BCVA between baseline and final follow up. The grey dashed line represents ‘no change’ while the black correlation line illustrates the subtle change. The measurement of each patient at each visit is depicted as a function of age in (B). (C) Correlation between EZ length and age. (D) EZ constriction rate (change in size divided by time between visits) as a function of age. Both (C) and (D) illustrate that the degeneration starts rapidly with later, slower decline. (E) and (F) illustrate the same changes in hyperAF ring area.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Hum. Mol. Genet.