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Figure 2

ID: ZDB-IMAGE-200725-22
Publication: Toms et al., 2020 - Clinical and preclinical therapeutic outcome metrics for USH2A-related disease
All Figures: Figures for Toms et al., 2020

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Figure 2

Visual acuity, EZ and hyperautofluorescent (hyperAF) ring measurements with age in USH2A patients. (A) and (B) Change in visual acuity over the observation period. (A) illustrates the change in BCVA between baseline and final follow up. The grey dashed line represents ‘no change’ while the black correlation line illustrates the subtle change. The measurement of each patient at each visit is depicted as a function of age in (B). (C) Correlation between EZ length and age. (D) EZ constriction rate (change in size divided by time between visits) as a function of age. Both (C) and (D) illustrate that the degeneration starts rapidly with later, slower decline. (E) and (F) illustrate the same changes in hyperAF ring area.

Acknowledgments

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