FIGURE

Fig. 6

ID

ZDB-FIG-200711-18

Publication

Castanon et al., 2020 - Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish

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Fig. 6

Alignment of F-actin and Antxr2a caps with the division plane requires sphingolipids.

a, c Polar graphs showing the frequency distribution of the angle between the F-actin cap (a) or the Antxr2a cap (c) with respect to the mitotic plane (green line in Fig. 5b, e). b, d Polar graphs showing the frequency distribution of the angle between the plane of division and the plane of the embryonic axis in epiblast cells expressing either Lifeact-mRFP biosensor (b) or Antxr2a-eYFP (d) in control and sptlc1 morphant embryos. χ² test was used (see Supplementary Table 1). n (number of cells analyzed) over N (number of embryos). DP division plane. Source data are provided as a Source Data file.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-sptlc1 AB + MO2-sptlc1 AB + MO3-sptlc1
Knockdown Reagents:	MO1-sptlc1 MO2-sptlc1 MO3-sptlc1
Observed In:	epiblast mitotic spindle
Stage:	Shield

Phenotype Detail

Acknowledgments

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