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Fig. 3

ID

ZDB-FIG-200615-20

Publication

Wang et al., 2020 - Metformin fights against radiation-induced early developmental toxicity

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Fig. 3

MET mitigates radiation-induced deformation of zebrafish larvae. (A) Effects of MET (2 mg/mL) on the rate of larvae with normal heart after radiation exposure (5.2 Gy). (B) The proportion of each level of spine bending in the total curvature between IR and MET group. (C) Representative images of the effects of MET on the pericardial edema in zebrafish larvae. (D) Effects of MET (2 mg/mL) on the rate of larvae with normal notochord after radiation exposure (5.2 Gy). (E) The proportion of each level of pericardial edema in the total pericardial edema between IR and MET group. (F) Representative images of the effects of MET on the spine bending in zebrafish larvae. Each experiment was repeated at least three times and each treatment group contains 108 zebrafish larvae divided into nine parallel groups. The data were presented as mean ± SEM. Student's t-test, *P < 0.05, **P < 0.01, ***P < 0.001.

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