FIGURE

Fig. 3

ID
ZDB-FIG-200605-23
Publication
Xia et al., 2020 - ube3d, a New Gene Associated with Age-Related Macular Degeneration, Induces Functional Changes in Both In Vivo and In Vitro Studies
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Fig. 3

Knockdown of ube3d Causes Increases Cell Death in the Eye

(A) TUNEL staining revealed few apoptotic cells (arrows) in the eyes of WT 72-hpf larvae. (B) Enlargement of (A). (C) TUNEL staining revealed an increase in apoptotic cells (arrows) in the eyes of e2-MO 72-hpf larvae. (D) Enlargement of (C). (E) A graphical representation demonstrating that the number of apoptotic cells in e2-MO 72-hpf larvae (21.0 ± 2.2) was significantly higher than the number in WT larvae (6.0 ± 2.6). The data are presented as the mean ± SD. ∗p < 0.05. Scale bars represent 250 μm (A and C) and 70 μm (B and D).
Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage: Protruding-mouth

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Mol Ther Nucleic Acids
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