FIGURE

Fig. 1

ID

ZDB-FIG-200605-21

Publication

Xia et al., 2020 - ube3d, a New Gene Associated with Age-Related Macular Degeneration, Induces Functional Changes in Both In Vivo and In Vitro Studies

Other Figures

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Fig. 1

Knockdown of ube3d Delays Zebrafish Eye Development and Reduces Eye Size

(A) Live images of WT 24-hpf larvae. (B Enlargement of (A) with the 3.2 magnification. (C) Live images of e2-MO 24-hpf larvae. (D) Enlargement of (C) with the 3.2 magnification. (E) Live images of WT 120-hpf larvae. (F) Live images of e2-MO 120-hpf larvae. (G) At 120 hpf, the percentage of small eyes in e2-MO larvae was significantly higher than the percentage in WT larvae. (H) At 120 hpf, eye size in e2-MO larvae was significantly smaller than eye size in WT larvae. The data are presented as the mean ± SD. ∗p < 0.05. Scale bars represent 400 μm (A and C), 125 μm (B and D), and 500 μm (E and F).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TU + MO1-ube3d
Knockdown Reagent:	MO1-ube3d
Observed In:	eye eye development
Stage Range:	Prim-5 to Day 5

Phenotype Detail

Acknowledgments

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