FIGURE

Figure 6

ID

ZDB-FIG-200326-6

Publication

L et al., 2020 - ZnO Nanoparticles Induced Caspase-Dependent Apoptosis in Gingival Squamous Cell Carcinoma through Mitochondrial Dysfunction and p70S6K Signaling Pathway

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Figure 6

Effects of ZnO-NPs on the activation of mTOR and p70S6K in human GSCC cells. (a) Quiescent Ca9-22 cells were treated with or without culture medium (10% fetal bovine serum (FBS)) in the absence (CTL) or presence of ZnO-NPs (20 µg/mL) or rapamycin (10 µM). (b) Quiescent OECM-1 cells were treated with ZnO-NPs (50 µg/mL). Then, cells were harvested and lysed for the detection of p-mTOR and p-p70S6K by Western blot analysis. Image-Pro Plus processing software quantified the relative level of phosphorylated protein. Data represent the mean ± SEM of five independent experiments. * p < 0.05 compared with the control group.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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