FIGURE

Figure 2

ID

ZDB-FIG-200325-24

Publication

Xiao et al., 2020 - Structural Characteristics and Hypolipidemic Activity of Theabrownins from Dark Tea Fermented by Single Species Eurotium cristatum PW-1

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Figure 2

Hypolipidemic effect of theabrownins (TBs) and fractionated theabrownin samples with different molecular weights in high-fat-induced obesity zebrafish. (A) Experimental outline of zebrafish model. (B) Zebrafish stained with oil red O and visualized under a microscope magnified 30 times. (C–E) Relative lipid accumulation in zebrafish treated with different concentrations of theabrownins. Data were expressed as mean ± SEM (n = 6). *p-value < 0.05 and #p-value < 0.001 compared to high-fat diet (HFD) group. HFD, high-fat diet-induced obesity zebrafish. DMSO, vehicle control at 0.1% (v/v). Simvastatin, positive control at 0.06 μM. TBs-LT3k, TBs-3-10k, and TBs-10-30k represented the fractionated theabrownin samples with molecular weights: <3 kDa, 3–10 kDa, and 10–30 kDa, respectively. Scale bar, 500 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	high fat chemical treatment by environment: simvastatin, high fat
Observed In:	blood vessel lipid gut lipid whole organism lipid
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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