ZFIN Image: Xiao et al., 2020, Figure 2

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Figure Caption

Figure 2

Hypolipidemic effect of theabrownins (TBs) and fractionated theabrownin samples with different molecular weights in high-fat-induced obesity zebrafish. (A) Experimental outline of zebrafish model. (B) Zebrafish stained with oil red O and visualized under a microscope magnified 30 times. (C–E) Relative lipid accumulation in zebrafish treated with different concentrations of theabrownins. Data were expressed as mean ± SEM (n = 6). *p-value < 0.05 and #p-value < 0.001 compared to high-fat diet (HFD) group. HFD, high-fat diet-induced obesity zebrafish. DMSO, vehicle control at 0.1% (v/v). Simvastatin, positive control at 0.06 μM. TBs-LT3k, TBs-3-10k, and TBs-10-30k represented the fractionated theabrownin samples with molecular weights: <3 kDa, 3–10 kDa, and 10–30 kDa, respectively. Scale bar, 500 μm.

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Phenotype details

Acknowledgments

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