Fig. 4
- ID
- ZDB-FIG-190913-70
- Publication
- Toms et al., 2019 - Phagosomal and mitochondrial alterations in RPE may contribute to KCNJ13 retinopathy
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Increased mitochondrial size in the retinal pigment epithelium (RPE) of obetd15 zebrafish. Mitochondrial size in the wild-type (WT) RPE at (a) 3 months post-fertilisation (mpf), (c) 6 mpf and (e) 12 mpf shows a decrease with age, while mitochondrial size in the obetd15 RPE at (b) 3 mpf, (d) 6 mpf and (f) 12 mpf shows an increase with age. Mitochondrial area measured from TEM images displayed on bar chart (g). Results are mean ± SEM. 13 mitochondria measured per WT and mutant age group. Statistical significance relative to WT of different ages †p < 0.05, ††p < 0.01. Statistical significance relative to WT against obetd15 of the same age. ***p < 0.001. Scale bar = 200 nm. |
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Observed In: | |
Stage: | Adult |