FIGURE

Fig. 2

ID

ZDB-FIG-190807-26

Publication

Mishra et al., 2019 - Zebrafish model of amyloid light chain cardiotoxicity: regeneration vs degeneration

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Fig. 2

Human LC protein is expressed in the liver and secreted into circulation. The human λ LC protein was detected in the liver of transgenic fish by immunohistochemistry (red staining). Scale bar represents 30 µm (A). Human λ LC protein is detectable in the serum from transgenic fish at 2 yr of age (B). Quantification of serum-free LC (sFLC) levels using recombinant H7 protein (rLC) as a standard for quantification (***P < 0.001) (C). A concentration (125 µg/ml) comparable to patients with AL amyloidosis was detectable in the serum. Con, control; TG, transgenic.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Am. J. Physiol. Heart Circ. Physiol.