FIGURE

Fig. 4

ID

ZDB-FIG-190807-28

Publication

Mishra et al., 2019 - Zebrafish model of amyloid light chain cardiotoxicity: regeneration vs degeneration

Other Figures

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Fig. 4

Early signs of functional as well as cellular compensation begin in AL-LC transgenic fish embryos. Increased proliferation as indicated by increased EdU-labeled nuclei (green) were detectable in the 48 hpf transgenic zebrafish hearts compared with control hearts (*P = 0.04) (A). Dimensional analysis to measure cardiac function was performed at 48 hpf as previously described in (23) revealing an increase in stroke volume (*P = 0.03, left) while maintaining a comparable heart rate (B). bpm, beats/min; Con, control; EdU, 5-ethynyl-2′-deoxyuridine; hpf, hours postfertilization; TG, transgenic.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	bw22Tg; bw23Tg
Observed In:	heart cell population proliferation heart contraction
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Am. J. Physiol. Heart Circ. Physiol.